Package: EMMREML
Type: Package
Version: 5.2
Date: 2026-09-29
Title: Fitting Mixed Models with Known Covariance Structures and GWAS
Author: Deniz Akdemir, Okeke Uche Godfrey
Maintainer: Deniz Akdemir <deniz.akdemir.work@gmail.com>
Description: An improved mixed model solver that handles a variety of
        covariance structures. The main functions are 'emmreml',
        'emmremlMultiKernel', and 'emmremlMultivariate'. The 'emmreml'
        function solves mixed models with known covariance structure
        using the 'EMMA' algorithm. 'emmremlMultiKernel' allows for
        fitting models with multiple random components with known
        covariance structures. The 'emmremlMultivariate' function
        solves multivariate Gaussian mixed models with known covariance
        structures using the 'ECM' algorithm. The package now offers
        both the original matrix interface (fully backward compatible
        with v3.1) and a modern formula interface. The
        'emmremlMultivariate' function restores 'Gpred' and all test
        outputs from v3.1 while fixing ECM convergence. The new 'gwas'
        function provides genome-wide association studies with mixed
        models, including an accelerated algorithm and visualization
        options.
Depends: R (>= 3.5.0), Matrix, stats
Imports: methods
Suggests: knitr, rmarkdown, testthat, ggplot2, MASS, data.table,
        viridis, impute
License: GPL-2
NeedsCompilation: no
Encoding: UTF-8
RoxygenNote: 7.3.3
Additional_repositories: https://bioconductor.org/packages/release/bioc
VignetteBuilder: knitr
URL: https://github.com/dakdemir/EMMREML
BugReports: https://github.com/dakdemir/EMMREML/issues
Repository: https://denizakdemir.r-universe.dev
Date/Publication: 2026-09-30 08:39:51 UTC
RemoteUrl: https://github.com/denizakdemir/emmreml
RemoteRef: HEAD
RemoteSha: 876aa2b4d4e21c62d5491c38faf21858400c7ec4
Packaged: 2026-09-30 14:41:11 UTC; root